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Cerebellar neurometabolite abnormalities
in pediatric attention/deficit hyperactivity disorder: a proton
MR spectroscopic study
Soliva JC, Moreno A, Fauquet J, Bielsa A, Carmona S, Gispert JD, Rovira M, Bulbena A, Vilarroya O,
Neurosci Lett. 2010 Feb 5;470(1):60-4. Epub 2009 Dec 29
[abstract]
Vestibular Function, Sensory Integration, And Balance Anomalies: A
Brief Literature Review
SOLAN, O.D., M.A., HAROLD A., SHELLEY-TREMBLAY,
Ph.D., JOHN, LARSON, O.D., Psy.D., STEVEN, (2007), Review
Optom Vis Dev 2007 Volume 38 (1), pp. 1-5
Dyslexia and the Cerebellar Deficit Hypothesis
BEATON,
ALAN A. (2002), Cortex, 2002, 38, pp. 479-490
[abstract]
Interactions of Task Demands, Performance and Neurology
DRAKE,
STEPHEN (1993), Vol. 1 No. 4 (August,
1993), pp. 3-5
Anatomical Correlates of Dyslexia: Frontal and Cerebellar
Findings
ECKERT, MA, LEONARD, CM, RICHARDS, TL, AYLWARD, EH, THOMSON,
J, BERNINGER, VW (2003), Brain 2003 Feb; 126 (Pt 2)
pp. 482-94
This study may be the first to show that anomalies in a cerebellar-frontal
circuit are associated with rapid automatic naming and the double-deficit
subtype of dyslexia. [abstract]
The Well Balanced Child Movement and Early Learning
GODDARD BLYTHE, SALLY (2004), Hawthorn Press, Stroud, UK
Neurological Dysfunction as a Significant Factor in Children Diagnosed
with Dyslexia
GODDARD BLYTHE, SALLY (2001), 5th
BDA International Conference, pp. 1-14
Cerebellar Function, Dyslexia and Articulation Speed
KASSELIMIS, D.S,
MARGARITY, M., VLACHOS, F. (2007), Child Neuropsychology,
October 12, 2007
The present study provides clues to support the cerebellar
deficit hypothesis and the possible relationship between reading
impairment and speed of articulation. [abstract]
The Effect of Treatment of
Dyslexic Children on Self-Esteem and Behavior — Dissertation
LEVINSON, J.V., STRICKER, G., & LEVINSON,
H.N. (2003), The
Gordon F. Derner Institute of Advanced Psychological Studies, Adelphi
University
Review of Current Concepts Regarding the Cerebellum
MERHI,
MD, DIANA M.B.B.S (Syd), DCH (2003), May 2003, pp.
1-7
Balance In Search of the Lost Sense
McCREDIE, SCOTT (2007),
Little, Brown and Company, New York
The Antidepressant Efficacy of the Anticholinergic Scopolamine
NIH
CLINICAL RESEARCH STUDIES, Protocol Number: 06-M-0234
The Association of Abnormal Cerebellar Function
in Children with Developmental Coordination Disorder and Reading
Difficulties
O’HARE, A.,
KHALID, S. (2002), Dyslexia, Oct-Dec;8(4), pp. 234-248
This study confirms that children with DCD should
be assessed for difficulties in phonological awareness. Additionally,
children aged between 7 and 12 years are on the whole, highly competent
in a range of gross motor skills and further study might determine
whether a simple parental questionnaire might detect children who
would benefit from further assessment. The study also suggests that
all the children with DCD have cerebellar dysfunction and further
work with a larger group might determine particular patterns associated
with reading delay. [abstract]
Evidence from Magnetic Resonance Studies
for Cerebellar Involvement in Dyslexic Dysfunction
C.RAE, J.H. HARASTY, T. DJENDROWSKJI, J.
TALCOTT, J. SIMPSON, A. BLAMIRE, R. M. DIXON, M. LEE, C. H. THOMPSON,
P. STYLES, A. J. RICHARDSON AND J. F. STEIN (2001), 5th
BDA International Conference, pp. 1-10
Neurological and physiological deficits have been reported
in the brain in developmental dyslexia. The temporoparietal cortex
has been directly implicated in dyslexic dysfunction, and substantial
indirect evidence suggests that the cerebellum is also implicated.
We wanted to find out whether the neurological and physiological
deficits manifested as biochemical changes in the brain. [abstract]
Disorders of the Cerebellum:
Ataxia, Dysmetria of Thought, and the Cerebellar Cognitive Affective
Syndrome
SCHMAHMANN, M.D., JEREMY D. (2004), The
Journal of Neuropsychiatry & Clinical
Neurosciences 16, August 2004, pp. 367-368
Cognitive and emotional disorders may accompany cerebellar diseases
or be their principal clinical presentation, and this has significance
for the diagnosis and management of patients with cerebellar dysfunction.
[abstract]
Developmental trajectories of brain volume abnormalities in children
and adolescents with attention-deficit/hyperactivity disorder.
JAMA, 288, 1740-8.
Castellanos FX, et al. (2002).
Various anatomic brain abnormalities have been reported for attention-deficit/hyperactivity
disorder (ADHD), with varying methods, small samples, cross-sectional
designs, and without accounting for stimulant drug exposure. The objective
of this study was to compare regional brain volumes at initial scan and
their change over time in medicated and previously unmedicated male and
female patients with ADHD and healthy controls. The researchers concluded
that Developmental trajectories for all structures, except caudate, remain
roughly parallel for patients and controls during childhood and adolescence,
suggesting that genetic and/or early environmental influences on brain
development in ADHD are fixed, nonprogressive, and unrelated to stimulant
treatment. [abstract]
Deficits of motion transparency perception in adult developmental
dyslexics with normal unidirectional motion sensitivity.
Vision Res, 42, 1195-203. Hill GT, Raymond JE. (2002).
Even though a unidirectional motion task failed to reveal processing abnormalities
in adult dyslexics, the motion transparency task was effective at revealing
significant perceptual dysfunction, suggesting that performance on this
task is a better psychophysical indicator of visual motion deficits in
dyslexia. [abstract]
The role of the cerebellum in cognition and behavior:
a selective review.
J Neuropsychiatry Clin Neurosci,
12, 193-8. Rapoport, M., van Reekum, R., & Mayberg, H. (2000).
A study on the role of the cerebellum in cognition and behavior, highlighted
cognitive deficitis and personality changes associated with cerebellar
disease. [abstract]
Rational dosages of nutrients have a prolonged effect on learning
disabilities.
Altern Ther Health Med, 6, 85-91.
Carlton, R. M., Ente, G., Blum, L., Heyman, N., Davis, W., &
Ambrosino, S. (2000).
A study on the effects of certain nutrients on children with learning
disabilities showed significant academic and behavioral improvements within
a few weeks of treatment with nutrient supplements. [abstract]
Cerebellar deficiency model of dyslexia upheld.
Clinical Psychiatry News,
January 2000. Coffin J. M., Ph.D., King's College, PA (2000).
A study showed that dyslexic adults failed to learn an associative type
of eye blink conditioning learning that is controlled by the cerebellum.
Physiological and behavioral effects of an antivertigo
antihistamine in adults.
Percept Mot Skills, 88, 707-32.
Lauter, J. L., Lynch, O., Wood, S. B., & Schoeffler, L. (1999).
A study found physiological support for the use of an antimotion
sickness antihistamine to improve cognitive-related performance with
obvious implications in treating learning-disordered children. [abstract]
Association of abnormal cerebellar activation with motor
learning difficulties in dyslexic adults.
Lancet,
353, 1662-7. Nicolson, R. I., Fawcett, A. J., Berry, E. L., Jenkins,
I. H., Dean, P., & Brooks,
D. J. (1999).
A study found lower brain activation in dyslexic adults undertaking
tasks known normally to involve cerebellar activation. [abstract]
Does the cerebellum contribute to cognitive aspects
of speech production? A functional magnetic resonance imaging (fMRI)
study in humans.
Neurosci Lett, 247, 187-90.
Ackermann, H., Wildgruber, D., Daum, I., & Grodd, W. (1998).
Positron emission tomography studies suggest a contribution of the lateral
aspects of the right cerebellar hemisphere to higher level (cognitive)
aspects of speech production. [abstract]
Dysfunctional cortico-cerebellar circuits cause 'cognitive
dysmetria' in schizophrenia.
Neuroreport,
9, 1895-9. Wiser, A. K., Andreasen, N. C., O'Leary, D. S., Watkins,
G. L., Boles Ponto, L. L., & Hichwa, R. D. (1998).
Studies made point of a dysfunctional corticocerebellar circuit leading
to poorly coordinated mental activity ("cognitive dysmetria"),
which could explain the broad range of schizophrenic symptoms. [abstract]
Metabolic
abnormalities in developmental dyslexia detected by 1H magnetic resonance
spectroscopy.
Lancet, 351, 1849-52.
Rae, C., Lee, M. A., Dixon, R. M., Blamire, A. M., Thompson, C. H., Styles,
P., Talcott, J., Richardson, A. J., & Stein, J. F. (1998).
Using proton meagnetic resonance spectroscopy,
this study led to the conclusion that the cerebellum is involved in dyslexia.
[abstract]
The
cerebellar cognitive affective syndrome.
Brain, 121,
561-79. Schmahmann, J. D., & Sherman, J. C. (1998).
In a neuroimaging study of patients with Cerebellar diseases, researchers
found impariments of verbal fluency, abstract reasoning and working memory;
spatial cognition; inappropriate personality and behavior; and language
deficits such as agrammatism and dysprosodia. [abstract]
Cerebellum in attention-deficit hyperactivity disorder:
a morphometric MRI study.
Neurology,
50, 1087-93. Berquin, P. C., Giedd, J. N., Jacobsen, L. K., Hamburger,
S. D., Krain, A. L., Rapoport, J. L., & Castellanos, F. X. (1998).
Clinical, neuroanatomic, and functional brain-imaging studies suggest
a role for the cerebellum in cognitive functions including attention.
It was found that a cerebello-thalamo-prefrontal circuit dysfunction may
contribute to deficits encountered in ADHD. [abstract]
Attentional activation of the cerebellum independent
of motor involvement.
Science, 275, 1940-3.
Allen, G., Buxton, R. B., Wong, E. C., & Courchesne, E. (1997).
Magnetic resonance imaging was used to demonstrate that the cerebellum
is involved in diverse cognitive and noncognitive neurobehavioral systems,
with attention and motor systems each activating distinct cerebellar regions.
[abstract]
Cerebellar size and cognition: correlations with IQ,
verbal memory and motor dexterity.
Neuropsychiatry Neuropsychol Behav Neurol,
10, 1-8. Paradiso, S., Andreasen, N. C., O'Leary, D. S., Arndt, S., & Robinson,
R. G. (1997).
Results indicate that the cerebellum contributes to cognition and cerebellar
volume significantly correlated with the ability to retain already encoded
information- verbal and fine motor skills. [abstract]
Cerebellum implicated in sensory acquisition and discrimination
rather than motor control.
Science,
272, 545-7. Gao, J. H., Parsons, L. M., Bower, J. M., Xiong, J., Li,
J., & Fox,
P. T. (1996).
Magnetic resonance imaging suggests that the cerebellum may be active
during motor, perceptual, and cognitive performance. [abstract]
Role of the cerebellum in visual guidance of movement.
Physiol Rev, 72, 967-1017.
Stein, J. F., & Glickstein, M. (1992).
This review shows that the cerebellum plays a crucial part in the visual
guidance of ocular and other movements- both reflex and voluntary. [abstract]
Abnormal visual-vestibular interaction and smooth pursuit
tracking in psychosis: implications for cerebellar involvement.
J Psychiatry Neurosci,
16, 30-40. Cooper, P. M., & Pivik, R. T. (1991).
Findings suggest that cerebellar dysfunction may contribute to irregularities
in smooth pursuit tracking and fixation suppression found in psychotic
patients. [abstract]
The human cerebro-cerebellar system: its computing,
cognitive, and language skills.
Behav Brain Res,
44, 113-28. Leiner, H. C., Leiner, A. L., & Dow, R. S. (1991).
Results of a study suggested that the cerebellum contributes to the learning
of cognitive and language skills, as well as its acknowledged traditional
role in motor functions. [abstract]
